Maintenance Therapy Improves Overall Survival in AML
نویسندگان
چکیده
منابع مشابه
Radiation therapy reduces local failure and improves overall survival in sPNET.
To the Editor: We applaud the study by Fangusaro et al. [1] on the treatment of young patients with sPNET which continues to be a challenging disease requiring multi-disciplinary management. However, we fear that with the authors’ focus on intensive chemotherapy and autologous transplant they have underestimated the curative value of radiation therapy in this disease. It is true that 12/20 surv...
متن کاملacute myeloid leukemia (aml): the role of maintenance chemo¬therapy
maintenance treatment for patients with acute myeloid leukemia (aml) in remission has recently been controversially discussed and even abandoned by several groups. an analysis of 16 published multicenter trials, however, revealed the highest probabilities of relapse free survival (rfs) in the range of 35-42 % at 4-5 years only in patients assigned to maintenance treatment when adult age and int...
متن کاملCDKN2B methylation correlates with survival in AML patients
Aberrant DNA methylation has been reported as an important phenotype in acute myeloid leukemia. However the clinical significance of methylation changes has not been clear yet. In this study methylation Specific Melting Curve Analysis (MS-MCA) and real time PCR was used to assess the CDKN2B promoter hyper-methylation and gene expression in 59 Iranian acute myeloid leukemia (AML) patients. The i...
متن کاملCLINICAL TRIALS AND OBSERVATIONS Maintenance therapy with thalidomide improves survival in patients with multiple myeloma
Michel Attal, Jean-Luc Harousseau, Serge Leyvraz, Chantal Doyen, Cyrille Hulin, Lofti Benboubker, Ibrahim Yakoub Agha, Jean-Henri Bourhis, Laurent Garderet, Brigitte Pegourie, Charles Dumontet, Marc Renaud, Laurent Voillat, Christian Berthou, Gerald Marit, Mathieu Monconduit, Denis Caillot, Bernard Grobois, Herve Avet-Loiseau, Philippe Moreau, and Thierry Facon, for the Inter-Groupe Francophone...
متن کاملMaintenance therapy with alternate-day prednisone improves survival in multiple myeloma patients.
The role of maintenance therapy in multiple myeloma is controversial. Recent studies have shown an improvement in both progression-free and overall survival for patients receiving maintenance treatment with a combination of interferon and glucocorticoids, compared with interferon alone. The role of glucocorticoids alone as maintenance therapy has not been previously addressed. We compared alter...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Oncology Times
سال: 2020
ISSN: 0276-2234
DOI: 10.1097/01.cot.0000653336.35007.90